Oct 20262026年10月
Two national invention patents were granted in 2026 — “Device for Rapid Slurry Replacement and Extrusion” (CN117206144B, granted 17 Jul 2026) and “Use of a Compound in Preparing a Drug for Removing Protein-Bound Uremic Toxins from Blood” (CN117752657B, granted 2 Jun 2026). Ten papers were published over 2025–2026 (six in 2025, four in 2026), including three conference papers at IEEE BIBM 2025 and BIC-TA 2025, and the models SPLiNet (protein–RNA interaction sites, Computational Biology and Chemistry) and ProtFormer-Site (protein–protein interaction sites, Interdisciplinary Sciences: Computational Life Sciences). Three further invention patent applications are under substantive examination.2026 年，实验室获授权国家发明专利 2 项：《浆料快速换料、挤出装置》（CN117206144B，授权公告日 2026-07-17）、《化合物在制备清除血液中蛋白结合尿毒素的药物中的应用》（CN117752657B，授权公告日 2026-06-02）。2025—2026 年共发表论文 10 篇（2025 年 6 篇、2026 年 4 篇），其中 IEEE BIBM 2025、BIC-TA 2025 会议论文 3 篇，另有蛋白质–RNA 相互作用位点预测模型 SPLiNet（Computational Biology and Chemistry）、蛋白质相互作用位点超快预测模型 ProtFormer-Site（Interdisciplinary Sciences: Computational Life Sciences）等。同期另有 3 项发明专利申请处于实质审查阶段。
Patent专利
Sep 20262026年9月
Seven students of the 2026 intake joined the lab in September 2026 — Zhe HU, Boyu GONG, Zhirui FU, Xiaocheng YAN, Zekai LI, Yuncheng MA and Jie YUAN. The group now counts 23 current graduate students, three of them Ph.D. students.2026 年 9 月，胡喆、龚博宇、傅志锐、颜晓程、李泽楷、马云程、袁劼 7 名 2026 级硕士研究生加入实验室。课题组在读研究生共 23 人，其中博士研究生 3 人、硕士研究生 20 人。
Life动态
Jul 20262026年7月
Lei WANG completed his postdoctoral term in July 2026 and joined the School of Chemistry, Central China Normal University, as an Associate Research Professor. He continues to work with the group as a co-supervising faculty member.2026 年 7 月，王雷博士完成博士后研究工作出站，加入华中师范大学化学学院任特任副研究员，并继续作为合作指导教师参与课题组研究工作。
Life动态
Jul 20262026年7月
Hongyang YE joined the lab as a research assistant in July 2026, working on protein language models, structure-aware representation learning and intelligent bioinformatics analysis.2026 年 7 月，叶宏阳加入实验室担任研究助理，从事蛋白质语言模型、结构感知表示学习与生物信息智能分析研究。
Life动态
Jun 20262026年6月
Xudong LI and Han ZHANG, undergraduates of the 2022 intake, were admitted in June 2026 to The Chinese University of Hong Kong (Hong Kong, China) to pursue a Ph.D. Xudong LI's undergraduate thesis was also named an Outstanding Degree Thesis of Huazhong University of Science and Technology.2026 年 6 月，2022 级本科生李旭东、张晗被中国香港中文大学录取，攻读博士学位；李旭东的本科毕业论文获评华中科技大学优秀学位论文。
Award荣誉
Apr 20262026年4月
In April 2026, the lab was granted the software copyright of “MinZuGongTongTi AI Large-Model Software V1.0” (《民族共同体人工智能大模型软件 V1.0》), a large-language-model application software independently developed by the lab.2026 年 4 月，实验室获批《民族共同体人工智能大模型软件 V1.0》软件著作权。该软件为实验室自主研发的人工智能大模型应用软件。
Software软件著作权
Dec 20252025年12月
The IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2025), a CCF-B venue, was held in Wuhan on 15–18 December 2025. Our paper “ProtSSSD: A Novel Approach for Intrinsically Disordered Protein Region Prediction Using Protein Language Model” (Lei Wang, Zilu Zeng, Yan Wang, and Zhidong Xue; pp. 1860–1863) was accepted and presented at the conference. In the same month, “MS-Detector: A Hierarchical Deep Learning Method to Detect Muscle Strain Using Bilateral Symmetric Ultrasound Images of the Body” appeared in Diagnostics 15(23): 3087.2025 年 12 月 15—18 日，CCF-B 类会议 IEEE International Conference on Bioinformatics and Biomedicine（BIBM 2025）在武汉举行，王雷等人的论文 ProtSSSD: A Novel Approach for Intrinsically Disordered Protein Region Prediction Using Protein Language Model 被会议录用（pp. 1860–1863）并在会上报告。同月，MS-Detector: A Hierarchical Deep Learning Method to Detect Muscle Strain Using Bilateral Symmetric Ultrasound Images of the Body 在 Diagnostics 15(23): 3087 发表。
Paper论文
Nov 20252025年11月
The 20th International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA 2025) was held in Wuhan on 7–9 November 2025, with the proceedings published by Springer in the Communications in Computer and Information Science series. Two papers from the group were presented — “An Effective DNA Storage for Contour-Based Image” (Chunxia Ge, Xiaosheng Dong, and Zhidong Xue; pp. 59–66) and “Protein-Protein Contact Prediction Using Structure-Informed Sequences and Protein Language Models” (Qiyuan Huang, Lei Wang, Zhihong Zhang, Jingjing Zhao, and Zhidong Xue; pp. 99–107).2025 年 11 月 7—9 日，第 20 届 Bio-Inspired Computing: Theories and Applications（BIC-TA 2025）在武汉举行，会议论文集由 Springer CCIS 出版。实验室两篇论文在会上报告：An Effective DNA Storage for Contour-Based Image（pp. 59–66）、Protein-Protein Contact Prediction Using Structure-Informed Sequences and Protein Language Models（pp. 99–107）。
Paper论文
Jul 20252025年7月
“Exploring ProtFlash: An Efficient Approach to Protein Data Analysis” by Lei Wang, Zhidong Xue and Yan Wang was published in Methods in Molecular Biology vol. 2941 (pp. 59–70) on 3 July 2025 — a step-by-step guide to the lightweight protein language model ProtFlash, from embedding generation to LoRA fine-tuning. In June, “High-precision screening of occupational chronic lead poisoning with machine-learning-enhanced LIBS” (Rui Zhang, Lizhu Kang, Zhijie Huang, Wenhao Yan, Zhanjian Lin, Ji Chen, Bing Lu, Zhidong Xue and Xiangyou Li) appeared in Spectroscopy and Spectral Analysis 45(6): 1648–1656, combining PCA with SVM and BPNN models to screen occupational chronic lead poisoning from whole-blood LIBS spectra, reaching 95.56% classification accuracy with BPNN.2025 年 7 月 3 日，王雷、薛志东、王燕撰写的 Exploring ProtFlash: An Efficient Approach to Protein Data Analysis 在 Methods in Molecular Biology 第 2941 卷出版（pp. 59–70），系统介绍轻量级蛋白质语言模型 ProtFlash 的嵌入生成与 LoRA 微调方法。同年 6 月，高精度职业性慢性铅中毒筛查：机器学习增强的 LIBS 技术应用 在《光谱学与光谱分析》45(6): 1648–1656 发表，以 PCA 结合 SVM、BPNN 从全血 LIBS 光谱中筛查职业性慢性铅中毒，BPNN 分类准确率达 95.56%。
Paper论文
Feb 20242024年2月
NeuroPep 2.0 published in Journal of Molecular Biology — the updated neuropeptide & receptor annotation database is now availableNeuroPep 2.0 在 Journal of Molecular Biology 发表，神经肽与受体注释数据库更新版现已开放使用
Paper论文
Jan 20242024年1月
DeepNeuropePred published in Computational and Structural Biotechnology Journal — robust neuropeptide cleavage-site prediction from protein language modelsDeepNeuropePred 在 Computational and Structural Biotechnology Journal 发表，利用蛋白质语言模型实现稳健的神经肽切割位点预测
Paper论文
Oct 20232023年10月
ProtFlash published in Cell Reports Physical Science — a lightweight protein language model deciphering the protein landscapeProtFlash 在 Cell Reports Physical Science 发表，以轻量级蛋白质语言模型解读蛋白质序列空间
Paper论文
Mar 20232023年3月
NeuroPred-PLM published in Briefings in Bioinformatics — interpretable and robust neuropeptide prediction with protein language modelsNeuroPred-PLM 在 Briefings in Bioinformatics 发表，基于蛋白质语言模型实现可解释、稳健的神经肽预测
Paper论文