Bioactive peptide information

BP1218

Name

DELTA-stichotoxin-She4b

Organism

Stichodactyla helianthus

Family

actinoporin family

Classification

Toxin and venom peptide

UniProt ID

ACTP2_STIHL

GO ID	GO Term	Definition	Evidence
GO:0005576	Cellular Component	extracellular region	IEA
GO:0042151	Cellular Component	nematocyst	IEA
GO:0044218	Cellular Component	other organism cell membrane	IEA
GO:0046930	Cellular Component	pore complex	IEA
GO:0015267	Molecular Function	channel activity	IEA	more>>
GO:0006812	Biological Process	cation transport	IEA
GO:0052331	Biological Process	hemolysis in other organism involved in symbiotic interaction	IEA
GO:0046931	Biological Process	pore complex assembly	IEA	less<<

Modification

Length

175

Sequence

ALAGTIIAGA  SLTFQVLDKV  LEELGKVSRK  IAVGIDNESG  GTWTALNAYF  RSGTTDVILP  EFVPNTKALL
YSGRKDTGPV  ATGAVAAFAY  YMSSGNTLGV  MFSVPFDYNW  YSNWWDVKIY  SGKRRADQGM  YEDLYYGNPY
RGDNGWHEKN  LGYGLRMKGI  MTSAGEAKMQ  IKISR

Properties

View

Structure

PDB	Method	Resolution	Chain	Position
1GWY	X-ray	1.71 A	A/B	1-175
1O71	X-ray	2.26 A	A/B	1-175
1O72	X-ray	2.41 A	A/B	1-175
2L2B	NMR	-	A	1-175
2L38	NMR	-	A	1-175
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DSSP

Helix (H, G, I): 12.00%

Beta strand (B, E): 48.00%

Turn (S, T): 19.43%

Coil (C): 20.57%

1    ALAGTIIAGA  SLTFQVLDKV  LEELGKVSRK  IAVGIDNESG  GTWTALNAYF  RSGTTDVILP
       TT EEEGG  G  HHHHHHH  HHHT S SSE  EEEEEEEESS  S EEEEEEEE  EESB SS
61   EFVPNTKALL  YSGRKDTGPV  ATGAVAAFAY  YMSSGNTLGV  MFSVPFDYNW  YSNWWDVKIY
     SEE TTEEEE  EEEE  SSS      EEEEEEE  EETTSEEEEE  EEEE S  SS     EEEEEEE
121  SGKRRADQGM  YEDLYYGNPY  RGDNGWHEKN  LGYGLRMKGI  MTSAGEAKMQ  IKISR
     ES     HHH  HHHHHSS  E  E SS EEEEE  EETTEEEEEE  E SSSEEEEE  EEEE

Pfam

Accession NO.	Identifier	Description
PF06369	Anemone_cytotox	Sea anemone cytotoxic protein

SCOP

Class	Fold	Superfamily	Family
All beta proteins	Cytolysin/lectin	Cytolysin/lectin	Anemone pore-forming cytolysin

CATH

Class	Architecture	Topology	Homology
Mainly Beta	Sandwich	Mutm (Fpg) Protein; Chain: A, domain 2