Bioactive peptide information

BP0942

Name

Neutrophil defensin 2

Organism

Homo sapiens

Family

alpha-defensin family

Classification

Antimicrobial

UniProt ID

GO ID	GO Term	Definition	Evidence
GO:0035578	Cellular Component	azurophil granule lumen	TAS
GO:0070062	Cellular Component	extracellular exosome	IDA
GO:0005576	Cellular Component	extracellular region	TAS
GO:0005615	Cellular Component	extracellular space	IDA
GO:0005796	Cellular Component	Golgi lumen	TAS	more>>
GO:0019731	Biological Process	antibacterial humoral response	IDA
GO:0050832	Biological Process	defense response to fungus	IEA
GO:0050830	Biological Process	defense response to Gram-positive bacterium	IDA
GO:0051607	Biological Process	defense response to virus	IEA
GO:0045087	Biological Process	innate immune response	IDA
GO:0002227	Biological Process	innate immune response in mucosa	IDA
GO:0030520	Biological Process	intracellular estrogen receptor signaling pathway	IDA
GO:0031640	Biological Process	killing of cells of other organism	IEA	less<<

Modification

Length

Sequence

CYCRIPACIA GERRYGTCIY QGRLWAFCC

Properties

Disulfide bond

Structure

PDB	Method	Resolution	Chain	Position
1ZMH	X-ray	1.50 A	A/B/C/D	1-29
1ZMI	X-ray	1.15 A	A/B/C/D	1-29
1ZMK	X-ray	1.30 A	A/B	1-29
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DSSP

Helix (H, G, I): 0.00%

Beta strand (B, E): 55.17%

Turn (S, T): 20.69%

Coil (C): 24.14%

1 CYCRIPACIA GERRYATCIY QGRLWAFCC
EEESS T T EEEEEEE TTEEEEEE

Pfam

Accession NO.	Identifier	Description
PF00323	Defensin_1	Mammalian defensin

SCOP

CATH