Bioactive peptide information

BP0674

Name

Beta-insect excitatory toxin Bj-xtrIT

Organism

Hottentotta judaicus

Family

Sodium channel inhibitor family

Classification

Toxin and venom peptide

UniProt ID

SIXE_HOTJU

GO ID	GO Term	Definition	Evidence
GO:0005576	Cellular Component	extracellular region	IEA
GO:0008200	Molecular Function	ion channel inhibitor activity	IEA
GO:0006952	Biological Process	defense response	IEA

Modification

Length

Sequence

KKNGYPLDRN GKTTECSGVN AIAPHYCNSE CTKVYYAESG YCCWGACYCF GLEDDKPIGP MKDITKKYCD
VQIIPS

Properties

View

Disulfide bond

Structure

PDB	Method	Resolution	Chain	Position
1BCG	X-ray	2.10 A	A	1-76
4KYP	X-ray	1.70 A	A/B/C/D	1-76
Jmol._Canvas2D (Jmol) "jmolApplet0"[x]			spin cartoon wire ball&stick spacefill

DSSP

Helix (H, G, I): 25.97%

Beta strand (B, E): 25.97%

Turn (S, T): 18.18%

Coil (C): 29.87%

1    MKKNGYPLDR  NGKTTECSGV  NAIAPHYCNS  ECTKVYYAES  GYCCWGACYC  FGLEDDKPIG
      EEEE B  T  TS   B  TH  HHHSSHHHHH  HHHHTT  SE  EEEETTEEEE  EEEETTS B
61   PMKDITKKYC  DVQIIPS
        HHHHHHH

Pfam

Accession NO.	Identifier	Description
PF00537	Toxin_3	Scorpion toxin-like domain

SCOP

Class	Fold	Superfamily	Family
Small proteins	Knottins (small inhibitors, toxins, lectins)	Scorpion toxin-like	Long-chain scorpion toxins

CATH

Class	Architecture	Topology	Homology
Alpha Beta	2-Layer Sandwich	Defensin A-like