Bioactive peptide information

BP0446

Name

Basic phospholipase A2 notechis II-5

Organism

Notechis scutatus scutatus

Family

phospholipase A2 family

Classification

Toxin and venom peptide

UniProt ID

PA2B5_NOTSC

GO ID	GO Term	Definition	Evidence
GO:0005576	Cellular Component	extracellular region	IEA
GO:0072556	Cellular Component	other organism presynaptic membrane	IEA
GO:0005509	Molecular Function	calcium ion binding	IEA
GO:0004623	Molecular Function	phospholipase A2 activity	IEA
GO:0016042	Biological Process	lipid catabolic process	IEA

Modification

Length

119

Sequence

NLVQFSYLIQ CANHGRRPTR HYMDYGCYCG WGGSGTPVDE LDRCCKIHDD CYSDAEKKGC SPKMSAYDYY
CGENGPYCRN IKKKCLRFVC DCDVEAAFCF AKAPYNNANW NIDTKKRCQ

Properties

View

Disulfide bond

Structure

PDB	Method	Resolution	Chain	Position
2NOT	X-ray	3.00 A	A/B	1-119
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DSSP

Helix (H, G, I): 50.42%

Beta strand (B, E): 8.40%

Turn (S, T): 22.69%

Coil (C): 18.49%

1    NLVQFSYLIQ  CANHGRRPTR  HYMDYGCYCG  WGGSGTPVDE  LDRCCKIHDD  CYSDAEKKGC
      HHHHHHHHH  HHHTTSS GG  GGTTBTTTTT  S   S   SH  HHHHHHHHHH  HHHHHHHTT
61   SPKMSAYDYY  CGENGPYCRN  IKKKCLRFVC  DCDVEAAFCF  AKAPYNNANW  NIDTKKRCQ
      TTT    EE  EETTEEEE    SSSHHHHHHH  HHHHHHHHHH  HHS   GGGB  T  HHHHT

Pfam

Accession NO.	Identifier	Description
PF00068	Phospholip_A2_1	Phospholipase A2

SCOP

Class	Fold	Superfamily	Family
All alpha proteins	Phospholipase A2, PLA2	Phospholipase A2, PLA2	Vertebrate phospholipase A2

CATH

Class	Architecture	Topology	Homology
Mainly Alpha	Up-down Bundle	Phospholipase A2	Phospholipase A2