Bioactive peptide information

BP0914

Name

Orexin-B

Organism

Homo sapiens

Family

orexin family

Classification

Neuropeptide

UniProt ID

GO ID	GO Term	Definition	Evidence
GO:0030054	Cellular Component	cell junction	IEA
GO:0005829	Cellular Component	cytosol	IEA
GO:0005576	Cellular Component	extracellular region	TAS
GO:0048471	Cellular Component	perinuclear region of cytoplasm	IEA
GO:0098794	Cellular Component	postsynapse	IEA	more>>
GO:0005791	Cellular Component	rough endoplasmic reticulum	IEA
GO:0030141	Cellular Component	secretory granule	IEA
GO:0008021	Cellular Component	synaptic vesicle	TAS
GO:0042755	Biological Process	eating behavior	IEA
GO:0060079	Biological Process	excitatory postsynaptic potential	IEA
GO:0008156	Biological Process	negative regulation of DNA replication	IEA
GO:0043267	Biological Process	negative regulation of potassium ion transport	IEA
GO:0051970	Biological Process	negative regulation of transmission of nerve impulse	IEA
GO:0007218	Biological Process	neuropeptide signaling pathway	IEA
GO:0007200	Biological Process	phospholipase C-activating G-protein coupled receptor signaling pathway	IEA
GO:0051928	Biological Process	positive regulation of calcium ion transport	IEA
GO:0007204	Biological Process	positive regulation of cytosolic calcium ion concentration	IEA
GO:0051971	Biological Process	positive regulation of transmission of nerve impulse	IEA
GO:0007205	Biological Process	protein kinase C-activating G-protein coupled receptor signaling pathway	IEA
GO:0046928	Biological Process	regulation of neurotransmitter secretion	IEA
GO:0007268	Biological Process	synaptic transmission	TAS	less<<

Modification

Modification	Residue	Position
Methionine amide	Met	28

Length

Sequence

RSGPPGLQGR LQRLLQASGN HAAGILTM

Properties

Structure

DSSP

Helix (H, G, I): 57.14%

Beta strand (B, E): 0.00%

Turn (S, T): 25.00%

Coil (C): 17.86%

1 FSGPPGLQGR LQRLLQASGN HAAGILTM
S SSHHHH HHHHHHHTTT SHHHHH

Pfam

Accession NO.	Identifier	Description
PF02072	Orexin	Prepro-orexin

SCOP

Class	Fold	Superfamily	Family
Peptides	Peptide hormones	Peptide hormones	Peptide hormones

CATH