Bioactive peptide information

BP0200

Name

Interferon omega-1

Organism

Homo sapiens

Family

alpha/beta interferon family

Classification

Cytokine/Growth factor

UniProt ID

IFNW1_HUMAN

GO ID	GO Term	Definition	Evidence
GO:0005615	Cellular Component	extracellular space	IBA
GO:0005125	Molecular Function	cytokine activity	IBA
GO:0005126	Molecular Function	cytokine receptor binding	TAS
GO:0005132	Molecular Function	type I interferon receptor binding	IBA
GO:0002250	Biological Process	adaptive immune response	IBA	more>>
GO:0030183	Biological Process	B cell differentiation	IBA
GO:0042100	Biological Process	B cell proliferation	IBA
GO:0007050	Biological Process	cell cycle arrest	TAS
GO:0019221	Biological Process	cytokine-mediated signaling pathway	IBA
GO:0051607	Biological Process	defense response to virus	IEA
GO:0006959	Biological Process	humoral immune response	IBA
GO:0002323	Biological Process	natural killer cell activation involved in immune response	IBA
GO:0033141	Biological Process	positive regulation of peptidyl-serine phosphorylation of STAT protein	IBA
GO:0043330	Biological Process	response to exogenous dsRNA	IBA
GO:0009615	Biological Process	response to virus	TAS
GO:0002286	Biological Process	T cell activation involved in immune response	IBA	less<<

Modification

Length

174

Sequence

LGCDLPQNHG  LLSRNTLVLL  HQMRRISPFL  CLKDRRDFRF  PQEMVKGSQL  QKAHVMSVLH  EMLQQIFSLF
HTERSSAAWN  MTLLDQLHTG  LHQQLQHLET  CLLQVVGEGE  SAGAISSPAL  TLRRYFQGIR  VYLKEKKYSD
CAWEVVRMEI  MKSLFLSTNM  QERLRSKDRD  LGSS

Properties

View

Disulfide bond

Structure

DSSP

Helix (H, G, I): 53.11%

Beta strand (B, E): 0.00%

Turn (S, T): 12.43%

Coil (C): 34.46%

1    ADPLGCDLPQ  NHGLLSRNTL  VLLHQMRRIS  PFLCLKDRRD  FRFPQEMVKG  SQLQKAHVMS
              S  TTHHHHHHHH  HHHHHT  S   GGGGSTT         TT          HHHHHH
61   VLHEMLQQIF  SLFHTERSSA  AWQMTLLDQL  HTGLHQQLQH  LETCLLQVVG  EGESAGAISS
     HHHHHHHHHH  HHHSSTTGGG  SS HHHHHHH  HHHHHHHHHH  HTT
121  PALTLRRYFQ  GIRVYLKEKK  YSDCAWEVVR  MEIMKSLFLS  TNMQERLRSK  DRDLGSS
     HHHHHHHHHH  HHHHHHHHHT  S HHHHHHHH  HHHHHHHHHH  TS

Pfam

Accession NO.	Identifier	Description
PF00143	Interferon	Interferon alpha/beta domain

SCOP

CATH