Bioactive peptide information

BP0181

Name

C-X-C motif chemokine 14

Organism

Homo sapiens

Family

intercrine alpha (chemokine CxC) family

Classification

Cytokine/Growth factor

UniProt ID

CXL14_HUMAN

GO ID	GO Term	Definition	Evidence
GO:0005615	Cellular Component	extracellular space	IEA
GO:0005794	Cellular Component	Golgi apparatus	IDA
GO:0008009	Molecular Function	chemokine activity	TAS
GO:0060326	Biological Process	cell chemotaxis	TAS
GO:0007267	Biological Process	cell-cell signaling	TAS	more>>
GO:0006935	Biological Process	chemotaxis	TAS
GO:0006955	Biological Process	immune response	IEA
GO:0048839	Biological Process	inner ear development	IEA
GO:0045662	Biological Process	negative regulation of myoblast differentiation	IEA
GO:2000503	Biological Process	positive regulation of natural killer cell chemotaxis	IEA
GO:0007165	Biological Process	signal transduction	TAS	less<<

Modification

Length

Sequence

SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE
KRRVYEE

Properties

View

Disulfide bond

Structure

DSSP

Helix (H, G, I): 25.64%

Beta strand (B, E): 19.23%

Turn (S, T): 30.77%

Coil (C): 24.36%

1    GSKCKCSRKG  PKIRYSDVKK  LEMKPKYPHC  EEKMVIITTK  SVSRYRGQEH  CLHPKLQSTK
            SSS  S   GGGEEE  EEE  SSTTS  SS  EEEEE   SSSTTTTSEE  EE TTSHHHH
61   RFIKWYNAWN  EKRRVYEE
     HHHHHHHHHH  HHHTT

Pfam

Accession NO.	Identifier	Description
PF00048	IL8	Small cytokines (intecrine/chemokine), interleukin-8 like

SCOP

CATH

Class	Architecture	Topology	Homology
Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)