Bioactive peptide information

BP0178

Name

C-X-C motif chemokine 5

Organism

Homo sapiens

Family

intercrine alpha (chemokine CxC) family

Classification

Cytokine/Growth factor

UniProt ID

CXCL5_HUMAN

GO ID	GO Term	Definition	Evidence
GO:0005576	Cellular Component	extracellular region	TAS
GO:0005615	Cellular Component	extracellular space	IBA
GO:0008009	Molecular Function	chemokine activity	TAS
GO:0045236	Molecular Function	CXCR chemokine receptor binding	IBA
GO:0060326	Biological Process	cell chemotaxis	TAS	more>>
GO:0007267	Biological Process	cell-cell signaling	TAS
GO:0070098	Biological Process	chemokine-mediated signaling pathway	IBA
GO:0006935	Biological Process	chemotaxis	TAS
GO:0007186	Biological Process	G-protein coupled receptor signaling pathway	IBA
GO:0006955	Biological Process	immune response	IBA
GO:0006954	Biological Process	inflammatory response	IBA
GO:0008284	Biological Process	positive regulation of cell proliferation	TAS
GO:0002690	Biological Process	positive regulation of leukocyte chemotaxis	IBA
GO:0032496	Biological Process	response to lipopolysaccharide	IBA
GO:0007165	Biological Process	signal transduction	TAS	less<<

Modification

Length

Sequence

AGPAAAVLRE LRCVCLQTTQ GVHPKMISNL QVFAIGPQCS KVEVVASLKN GKEICLDPEA PFLKKVIQKI
LDGGNKEN

Properties

View

Disulfide bond

Structure

DSSP

Helix (H, G, I): 19.23%

Beta strand (B, E): 21.79%

Turn (S, T): 21.79%

Coil (C): 37.18%

1    AGPAAAVLRE  LRCVCLQTTQ  GVHPKMISNL  QVFAIGPQCS  KVEVVASLKN  GKEICLDPEA
                    S SS        GGGEEEE  EEE   SS S  S EEEEEESS  S EEEE TTS
61   PFLKKVIQKI  LDGGNKEN
     HHHHHHHHHH  HHTTTT

Pfam

Accession NO.	Identifier	Description
PF00048	IL8	Small cytokines (intecrine/chemokine), interleukin-8 like

SCOP

CATH